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Monitor Carefully (two)diazepam will enhance the amount or influence of midazolam intranasal by impacting hepatic/intestinal enzyme CYP3A4 metabolism.crofelemer improves amounts of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Crofelemer has the potential to inhibit CYP3A4 at concentrations predicted within

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